In particular, the KEGG analysis indicated that changes in signaling pathways were mostly enriched in virus infection (Epstein–Barr virus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection), antigen processing and presentation, and immune-related pathways (NF-κB signaling pathway, Th17 cell differentiation and phagosome). This evidence concerns the gene NFKB1 and viral infectious disease.