The treatment of DLB includes cholinesterase inhibitors for cognitive and behavioral impairment symptoms of DLB: rivastigmine, galantamine and donepezil, memantine, atypical antipsychotic drugs for agitation, levodopa/carbidopa for parkinsonism, pimavanserin for psychosis, melatonin or clonazepam for RBD and personalized psycho-cognitive treatment [135,136,137]. The gene discussed is BCHE; the disease is Lewy body dementia.