Additionally, ACTL6A increases colon cancer invasion, metastasis, and epithelial mesenchymal transition (EMT) [18] and it was suggested that ACTL6A could be a regulator of enforces the progenitor state and a potential therapeutic target in hepatocellular carcinoma (HCC) [19,20,21]. The gene discussed is ACTL6A; the disease is hepatocellular carcinoma.