The reason of this discrepancy is unclear, but one possible explanation is that in BxPC-3 cells DF5 drastically decreases an enlarged population of cancer cells having stem-like properties, but only in part recognized by the selected surface markers, whereas RSV preferentially affects the stem-like population of BxPC-3 cells enriched for CD133 and EpCAM cancer stem cell markers. This evidence concerns the gene PROM1 and cancer.