HNF1B and ovarian cancer: In two separate large cohort studies, one on an Australian population known as Australian ovarian cancer women (AOCS) and in another study on a Japanese population known as high-volume Japanese university clinical network (JIKEI), the over-expression of HNF-1β was found to be in OCCC subtypes and have been associated with significantly longer PFS (p = 0.01) and OS (p = 0.02) [54,116].