AKT1 and colorectal carcinoma: According to a study by Han et al. [90], wogonoside prevented cell growth and induced mitochondria-mediated autophagy-related apoptosis in human LOVO CRC cells by controlling the phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)/p70S6K signaling pathway.