SCN4A and familial long QT syndrome: Given the association of paroxetine with both BrS and LQTS and its established inhibiting effect on neuronal NaV1.4, NaV1.7, and NaV1.8 channel function [32,33,34], the main objective of this study was to investigate the effect of paroxetine on the functioning of the highly homologous cardiac NaV1.5 channel.