VPS13D and Spastic paraplegia: In all homologs, pathogenic variants have been linked to different neurological disorders [2]: biallelic variants in VPS13A cause chorea-acanthocytosis [3] (OMIM: #200150), in VPS13B Cohen syndrome [4] (OMIM: #216550), in VPS13C early-onset parkinsonism [5] (OMIM: # 616840), and in VPS13D, as recently shown, spastic ataxia or spastic paraplegia [6,7] (OMIM: # 607317).