It can be caused by mutations in five different genes (PEX7, GNPAT, AGPS, FAR1, and PEX5 (long isoform) causing RCDP types 1–5, respectively), all involved in different peroxisomal steps of the biosynthesis pathway [2,3,4,5,6]. This evidence concerns the gene GNPAT and rhizomelic chondrodysplasia punctata.