PDCD1 and central nervous system cancer: In general, gliomas had lower transcript expression of SIRPA (gene encoding SIRPalpha) (Figure 7I) and higher of PD-L1 (CD274), PD-L2 (PDCD1LG2), TIM-3 (HAVCR2), PD-1 (PDCD1) (Figure 7B,D,F,H, respectively).