Therefore, in this context, in line with what was observed in glioblastoma stem cells [40], the functional interaction between an antisense lncRNA and its “sense” mRNA is a key event, but, contrary to the FOXM1-FOXM1-AS case described in the nuclear lncRNA paragraph, DDIT4-AS1, antisense to DDIT4, induces the downregulation of DDIT4 mRNA. Here, DDIT4 is linked to glioblastoma.