CD44 and bronchopulmonary dysplasia: In Caucasian subjects, rs1049269 is a known polymorphism associated with BPD development (OR, 3.21, 95% CI 1.51–6.82) [27]; however, a GWAS conducted in extremely low birthweight infants with BPD found no significant correlation between BPD and SNPs but found that multiple SNPs in adenosine deaminase, CD44, and other genes involved in pathways of lung development were more frequent in patients with BPD, with a significant increase in miR-219 and CD44 levels [28].