EIF2AK2 and myotonic dystrophy type 1: Additionally, the aberrant expression of other cell proliferation stimulators observed in DM1, such as protein kinase R (PKR), protein kinase R-like ER kinase (PERK), and pyruvate kinase M2 (PKM2), is also observed in cancer, which may explain why DM1 patients present with increased cancer susceptibility [128,129,130].