Thus, the increase in the prevalence of obesity in this age group is worrying, as this condition can lead to changes in the lipid profile, with an increase in the levels of total cholesterol, triglycerides, LDL and a reduction in HDL levels, in addition to arterial hypertension, resistance to insulin and diabetes, changes that have already been observed in adolescents [31,32,33,34,35,36]. This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.