Since this is the first study describing the utility of sFtl-1/PIGF ratio in the diagnosis and severity assessment of preeclampsia, which is directly related to maternal morbidity and mortality in our region, we presume that the results of our research regarding particular epidemiological aspects of this important pathologic condition, pointing out preventable causes and early diagnosis, will help in the implementation of targeted interventions, with a major clinical impact. Here, PIGF is linked to preeclampsia.