SLC23A3 and type 2 diabetes mellitus: In the case of type 2 diabetes, of the 11 genomic regions association with ascorbate plasma concentration in 80,983 cases and 842,909 noncases, the strongest signal was found with SLC23A1 [67], the vitamin C transporter SVCT1, with a significant signal also with SLC23A3, the orphan transporter SVCT3 [69].