IL1R1 and neoplasm: The higher infiltration of the tumor parenchyma by Il18r−/− CTLs was paralleled by a significantly higher average speed (8.05 μm/min) of Il18r−/− CTLs when compared to WT and Il1r−/− CTLs (WT: 4.83 μm/min, Il1r−/−: 4.85 μm/min) in the DSFC model (Figure 1D).