As limitations of our study, we (a) did not decipher whether or not the protective effects of CTRP9 in diabetic cardiomyopathy depended primarily on its impact on cardiomyocyte metabolism or on its anti-inflammatory nature,(b) we only investigated the effects of CTRP9 in one model of diabetic cardiomyopathy and (c) only in male mice. This evidence concerns the gene C1QTNF9 and diabetic cardiomyopathy.