In addition, analysis of myocardial fibrosis by Sirius red staining, of lipid deposition by oil red o staining and of oxidative damage by staining for 4-hydroynonenal (4-HNE) did not reveal any differences between WT, KO and HET or AVV-Luc and AAV-CTRP9 treatment during chow or HFD feeding (Figure 7E,F and Figure S3C,D). The gene discussed is C1QTNF9; the disease is Myocardial fibrosis.