On the other hand, novel aspects were uncovered, such as reduced expression of cardiomyocyte-specific genes, such as Actc1 or Gata4, or the reduced expression of splicing factors in the myocardium of CTRP9 KO mice that result mainly in exon skipping in genes related to mitochondria, autophagy and metabolism and might therefore contribute to the accelerated development of diabetic cardiomyopathy. This evidence concerns the gene C1QTNF9 and diabetic cardiomyopathy.