IFITM2 and infection: Since the support cells—similar to many other host cells—have evolved more potent defense mechanisms for the endosomal route of infection [102,107], for example, the antiviral IFITM2 gene is the most highly upregulated gene in support cells at 3 days after infection [108], this may lead to a lower efficiency in omicron infection of the support cells in the olfactory epithelium, and, therefore, reduced olfactory dysfunction [102,109].