Real-time cell analyses indicating that T98G glioblastoma cell migration or invasion was only induced in cells where SpastinM87_mutD protein was overexpressed (Figure 9) imply that Spastin would only induce cell migration or invasion in its phosphorylated form in MBD and, hence, was orientated to actin filaments owing to its interaction with Pin1. Here, PIN1 is linked to glioblastoma.