Investigations in mitotic cells have not proceeded beyond examining the function of Spastin in the ER tubular network; only a study performed by Draberova and colleagues (2011) revealed that Spastin levels are increased in glioblastoma cells interrelatedly with their invasion capacity and that it is co-localized with actin in migratory T98G glioblastoma cells [14], indicating that Spastin might also play a role in cell motility. Here, SPAST is linked to glioblastoma.