Nevertheless, upon closer inspection, an interesting pattern appears: Firstly, in the case of the two 7-year-old patients with ß-thalassemia major, the proportion of the total number of DDX4-positive cells was approximately 100 cells/mm2 higher than the proportion of the total number of PIWIL4-positive cells (see 1st and 2nd blue bars in Figure 6g vs. Figure 6h, and 1st vs. 2nd line of the calculated values in Figure 6i). This evidence concerns the gene PIWIL4 and thalassemia.