IL6 and ovarian cancer: The epithelial marker β-catenin is also reported to be downregulated similarly in ovarian cancer cells by treatment with TGF-β [40], but β-catenin was found to be upregulated by IL-8 [37,66] and nuclear translocation of β-catenin, which is also a form of change expected with EMT as reported in IL-6 treatment [77].