AKT1 and non-small cell lung carcinoma: Recently, we reported findings on how nicotinic acetylcholine receptors, tropomyosin receptor kinase B, and β-adrenergic receptors lead to regulation of EGFR and IGF-1R in NSCLC to affect phosphatidylinositol 3-kinase (PI3K)/AKT signaling and chemoresistance [6].