Among the changes in ETV6::RUNX1-like ALL patients, the following fusions are included: ETV6 and PMEL; IKZF1 and CDK2; ETV6 and BORCS5; SETD5 and IKZF1; ETV6 and NID1; ETV6 and CREBBP; ETV6 and BCL2L14; and ETV6 and MSH6. The gene discussed is IKZF1; the disease is acute lymphoblastic leukemia.