The full involvement of microglia in the neurodegenerative processes is still the subject of investigation [7], but chronic inflammatory activation may result in neuronal damage [6], and abnormal activation of microglia could contribute to the spread of alpha-synuclein and beta-amyloid plaques in the brain of PD and Alzheimer’s disease (AD) patients [8,9]. The gene discussed is SNCA; the disease is Alzheimer disease.