EGFR and neoplasm: In the univariate analysis, the associated factors were as follows: age > 65 years (p = 0.002), smoking history (p = 0.016), CEA level (p < 0.001), tumor size (p < 0.001), lepidic growth pattern in the tumor (p = 0.004), presence of pleural (p < 0.001) and lymphovascular (p < 0.001) invasion, N1 lymph node metastasis (p < 0.001), and EGFR mutations (p = 0.023).