Similar sensitization was seen in another study on ovarian cancer (HO8910 and SKOV3) in which the shRNA-mediated inhibition of MUS81 expression was associated with a sensitization to olaparib and camptothecin, together with an increase in the expression of the protein BM28 that is involved in early steps of DNA replication [44]. This evidence concerns the gene MCM2 and ovarian carcinoma.