As we have previously reported, MYCN expression is correlated with immune repression in different tumors, such as SCLC, NB, rhabdomyosarcoma (RMS), retinoblastoma (RB), Wilms’ tumor, T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (ALM) [70]. This evidence concerns the gene MYCN and acute lymphoblastic leukemia.