ALOX12 and glioblastoma: In GBM tumors, expression of 12S-LOX/ALOX12 and 12R-LOX/ALOX12B is not different from healthy brain tissue [8,9], nor is it associated with prognosis severity [9], nor is the expression of the receptor for 12S-HETE, i.e., GPR31, elevated and affecting prognosis [8,9].