All GBM lines express LTA4H, LTB4R1/BLT1, LTB4R2/BLT2, and CysLTR2, but only some lines express LTC4S [309], indicating heterogeneity in the production of cysteinyl-leukotrienes and 5-HETE by GBM cancer cells. The gene discussed is LTC4S; the disease is glioblastoma.