According to GEPIA and Seifert et al., there is a reduction in ACOT7 expression in GBM tumors relative to healthy brain tissue [8,9], where higher expression of this enzyme is associated with a worse prognosis for a GBM patient [9], suggesting the involvement of ACOT7 in tumorigenesis in GBM. The gene discussed is ACOT7; the disease is glioblastoma.