Reinforcing the idea that DPEITC can rescue different p53 mutants, we showed that DPEITC inhibited proliferation and induced apoptosis in HER2+ (SK-BR-3 and AU565) and Luminal A (T47D) breast cancer cells expressing different p53 structural mutants, p53R175H or p53L194F. The gene discussed is TP53; the disease is breast cancer.