CSCs are distinguished from normal cancer cells by activating signaling pathways (including Wnt/beta-catenin [9], Hedgehog [10], Notch [11], TGF-beta [12] and PI3K/AKT/mTOR [13]) and aberrantly expressing transcription factors (including SOX2, Nanog, OCT4 and MYC [14]), which are CSCs’ hallmarks. This evidence concerns the gene MYC and cancer.