Anatomic proclivity can occasionally be explained by chronic, local immunogenic exposure as evidenced by the well-known association of EATL with Celiac disease [52]; additionally, Kern et al. described a subtype of PTCL that expresses CD56, also known as neural cell adhesion molecule (NCAM), which is associated with an increased incidence of CNS (36%), GI (24%), and nasopharyngeal (24%) involvement [53]. Here, NCAM1 is linked to celiac disease.