ITIH1 and colorectal cancer: Among the mutated genes in the adenomatous tissue samples involved in our study, PCDHGB4 [56], AHRR [57], KIF4 [58,59], LPAR6 [22,60], NBPF1 [61], and NCEH1 [62] were already associated with colorectal cancer formation, while ANKRD30A [63], ITIH1 [64], and KIAA0556 [65] were related to other types of cancers.