For the CLL, c-CLL, and M-IGHV subsets, there was the presence of IgM mAbs against the hemolysin E protein of STY; while for p-CLL, CLL-TFT, and U-IGHV there was the presence of IgG mAbs against the outer membrane protein of STY. This evidence concerns the gene TBXT and B-cell chronic lymphocytic leukemia.