Using transcriptomic and genomic data available for 9801 tumors representing 32 different cancer types from The Cancer Genome Atlas (TCGA) PanCancer Atlas Studies, we assessed for associations between KYNU mRNA expression and presence of mutations in NFE2L2, the gene encoding for NRF2, or KEAP1. Of the 9801 analyzed tumors, 2.73% had NFE2L2 mutations, 2.67% had KEAP1 mutations, and 5.24% had either an NFE2L2 or a KEAP1 mutation. The gene discussed is NFE2L2; the disease is cancer.