Additionally, the transfection of miR-195 has also been reported to downregulate the mRNA and protein expression of PD-L1, therefore reducing the proliferation and migration of OCI-Ly10 cells (diffuse large B cell lymphoma), and also preventing OCI-Ly10 cells from immune escape while raising apoptotic ratio in those cells [28]. The gene discussed is CD274; the disease is diffuse large B-cell lymphoma.