A similar study performed by Lee et al. showed tandem decreases in MMP-9 mRNA levels following the inhibition of ERK1/2 phosphorylation in rhabdomyosarcoma, fibrosarcoma, bladder, colon, and prostate carcinoma cells [41], which is in accordance with the results for the NMIBC patients of this study. The gene discussed is MAPK3; the disease is rhabdomyosarcoma.