Consistently with the cellular origin of ES and the high level of stemness markers expressed by these tumour cells [48,49,50], no significant differentially expressed genes associated with pluripotency, ABC transporter and Wnt signalling pathways were identified in CD133-positive and CD133-negative cells (Figure 2B (TC-32) and Figure 2C (A673), Supplementary Data S4). The gene discussed is PROM1; the disease is neoplasm.