SLC7A11 and cancer: Cancer cells upregulate multiple amino acid transporters as a means to increase the influx of amino acids from circulation; this includes the transporters SLC7A5 (LAT1), SLC1A5 (ASCT2), SLC6A14 (ATB0,+), SLC7A11 (x-c), SLC38A5 (SNAT5) and SLC43A2 [1,2,3,4,5,6].