AFP and hepatocellular carcinoma: In Cox model 1 (Table 3), serum bilirubin level > 1.1 mg/dL, creatinine ≥ 1.2 mg/dL, AFP ≥ 20 ng/mL, vascular invasion, distant metastasis, ALBI grade 3, performance status 1, performance status 2–4, non-curative treatment, TTV > 100 cm3 were associated with decreased OS in HCC patients with ascites (all p < 0.001).