Anesthetic induction with a higher dosage of midazolam in patients undergoing thoracoscopic resections of lung cancer was reported to provide better inhibition of the production of serum TNF-α and remarkably decrease the requirement for anesthetics, which may stabilize the hemodynamics of patients in the perioperative period and mitigate the severity of postoperative pain [127]. The gene discussed is TNF; the disease is lung carcinoma.