An incessant low and chronic inflammation in CKD patients will activate the generation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and myeloperoxidase (MPO) by polymorphonuclear neutrophils and monocytes macrophages, which promotes the production of reactive oxygen species (ROS) and initiates a state of oxidative stress [62]. Here, MPO is linked to chronic kidney disease.