BRCA1 and neoplasm: Three germline BRCA1/2 large genomic rearrangements were detected in germline and tumour DNA using Myriad’s myChoice® CDx, including BRCA1 Exon 9-12 deletion (GIS 56), BRCA1 Exon 17 deletion (GIS 70) and BRCA2 Exon 14-16 deletion (GIS 36).