GPT and Decreased total leukocyte count: From a pool of five phase 1–3 clinical trials in China, the most common treatment-related adverse events were leukopenia (55.4%), alopecia (54.6%), neutropenia (50.6%), increased aspartate aminotransferase (49.7%), fatigue (46.3%), increased alanine aminotransferase (42.9%), and hypoesthesia (40.9%) [151].