CNN3 and benign prostatic hyperplasia: Of the 11 CAF proteins that showed a decrease in abundance in BPH-1 co-culture, seven were only significantly reduced in CAFs, not NPFs, when they were co-cultured: TAGLN, RAB5A, MGST1, MARCKS, CNN3, CALD1, and ITGAV (Figure 3D, Table 2).