Considering that IL-6 signalling is mainly mediated by the signal transducer and activator of transcription-3 (STAT3) pathway, we further explored whether an altered phosphorylated state of the tyrosine residue 705 (pY705) STAT3 protein may also influence the expression of TNFR2 phenotype in the ovarian cancer microenvironment. This evidence concerns the gene IL6 and ovarian cancer.