EGFR and neoplasm: An entirely unique set of 114 transcripts (24 decreased in recurrence, 90 increased in recurrence) was found to be differentially expressed (padj < 0.05, Table S4, volcano plot shown in Figure 3d) between primary and recurrent EGFR non-amplified tumours of the total 20,038 transcripts, suggesting that primary-recurrent tumour differences in transcriptome are generally distinct depending on EGFR amplification status.