The standard first-line molecular targeted therapy for advanced EGFR mutations in NSCLC patients is the EGFR-tyrosine kinase inhibitor (EGFR-TKI), which includes gefitinib, erlotinib, afatinib, dacomitinib, and osimertinib [2,3,4,5,6]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.