Other significant LOHs detected only in FTC patients, albeit less frequently, included the following regions: 1q21.1 (about 3.03 Mbp, most important genes: PDE4DIP, BCL9), 2q11.2 (over 4.2 Mbp, including ARID5A and COX5B genes), 3p12.2 (about 3.7 Mbp, including GBE1 gene), 8q11.1 (over 2.8 Mbp in size, including MCM4 and UBE2 genes), 14q23.3 (3.5 Mbp, including MAX, ATP6, EIF2, ARG2, RAD51B, and GPHN genes), 14q32.31 (over 2.8 Mbp, including HSP90, TRAF3, TNFA, APOPT1, and KIF26A), and 22q11.23 (0.82 Mbp, including GSTT1, GSTT2, and CABIN1 genes). The gene discussed is COX5B; the disease is thyroid cancer, nonmedullary, 2.