To verify the stimulating effect of ZA, purified T lymphocytes from healthy donors were co-cultured with CRC-TAF at different T:TAF ratios in the presence of 2.5 μM ZA, concentration in the range 1–5 μM reported as efficient in our previous papers [19,33], followed by the addition of IL-2. This evidence concerns the gene IL2 and colorectal carcinoma.